Surface Plasmon Resonance

Get an SPR Assay Quote

Tell us your target and analyte — we'll scope a label-free kon/koff/KD measurement and route it to a qualified lab in the network. No back-and-forth with sales, no vendor hunting.

5–7 days turnaround
Label-free detection
kon/koff/KD kinetic params

What you submit. What you get back.

Turnaround
5–7 business days
From purified protein receipt. Surface preparation and regeneration scouting included. Complex targets may require additional time.
Sample Requirements
~50 µg purified ligand
Purified protein for surface immobilization (biotinylated or amine-coupling). Analyte compound or protein at ≥95% purity. DMSO tolerance assessed per run.
Output Format
CSV + sensorgrams
Raw sensorgram data, reference-subtracted traces, 1:1 Langmuir kinetic fit, kon, koff, KD, Rmax, and chi-squared goodness of fit.

What we need to send you an accurate quote

Most SPR quotes are scoped within a day when we have these details up front. If you're not sure about something, submit anyway — the lab will follow up before committing to a run.

  • Target protein identity, construct, and species
  • Analyte identity — small molecule, peptide, or protein
  • Whether purified protein is already in hand or needs sourcing
  • Expected affinity range, if known (nM, µM, etc.)
  • Buffer or solubility constraints on the analyte
  • Target timeline for results

Who requests SPR quotes from Litmus

Hit Validation & Triage

Confirm binding to the intended target for computational hits before investing in cellular assays. Separate true binders from false positives early.

Lead Optimization & SAR

Measure how structural modifications affect kon, koff, and KD to guide medicinal chemistry decisions with quantitative biophysical data.

Fragment Screening

Screen fragment libraries against a target protein to identify low-affinity binders for FBDD programs that require biophysical confirmation.

Ready to scope your SPR run?

Start your request in the Litmus platform — tell us your target and analyte, and a qualified lab will confirm surface chemistry and turnaround.

Start Your SPR Quote →

Or email us directly. No spam, ever.